QUESTION
In a study of the adverse effects of x-rays among children, a retrospective cohort study was done using records from several large children’s hospitals for the period of 1980 to 1985. 10,000 children were selected as a representative population of ill children seen at the hospitals during that time. Subjects were classified according to whether or not they received an x-ray during their stay in the hospital and were followed from their hospital stay through 2005 for the development of cancer. During the follow-up period, 49 incident cancers occurred in 3,263 children who had received an x-ray, and 47 incident cancers occurred in the 6,737 children who had not received an x-ray during their hospitalization.What are the rates of cancer incidence in each exposure group?What is the attributable risk of cancer due to x-ray in this study population? What is the interpretation of this estimate?What is the risk ratio for the effect of exposure on the development of cancer in this study? What is the interpretation of this estimated ratio?
ANSWER:
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