What event in the mid-1400s caused Christian Europe to seek new ways t

What event in the mid-1400s caused Christian Europe to seek new ways to reach Asia for more direct and effective trading opportunities with Asia?

A) a political revolution in China
B) a massive earthquake in China
C) the fall of Constantinople to the political control of the Muslim Ottoman Turks
D) the decline of the city states of Italy, Genoa, especially Venice and Florence

ANSWER
Answer: C